Retatrutide 5mg 10mg mtengo wotsika mtengo

Dzina la malonda: Retatrutide

Kufotokozera: 5mg*10vial/kit 10mg*10vials/kit

MOQ: 1 kit

Mtengo: 5mg USD320/kit 10mg USD600/kit

Malo Ochokera: China

Retatrutide

Retatrutide (LY-3437943) ikukonzekera chithandizo cha matenda amtundu wa 2 shuga, obstructive sleep apnea, osteoarthritis, kunenepa kwambiri komanso matenda a chiwindi omwe si oledzera.The mankhwala ofuna kutumikiridwa kudzera subcutaneous ndi mtsempha wa magazi njira.Mankhwalawa amachitapo kanthu poyang'ana glucagon-ngati peptide 1 (GLP-1), insulinotropic polypeptide (GIP) yodalira glucose, ndi glucagon receptors.Ndi chinthu chatsopano cha mamolekyu.

Retatrutide imagwira ntchito pochiza kunenepa kwambiri poyang'ana mahomoni atatu owongolera njala: - GIP (gastric inhibitory peptide kapena glucose-dependent insulinotropic polypeptide) ndi incretin hormone yomwe imatulutsidwa m'matumbo mutadya.Retatrutide imapangitsa maselo a beta mu kapamba kuti atulutse insulini. Mankhwalawa ndi peptide yokhala ndi amino acid motsatizana.Ndi katatu ma hormone receptor agonist a GLP-1, GIP, ndi GCGR receptors.Zasonyezedwa kuti zikwaniritse zoposa 24% zimatanthauza kuchepetsa kulemera kwa anthu omwe alibe matenda a shuga kapena akuluakulu olemera kwambiri.

Retatrutide ndi yofanana ndi Ozempic, Wegovy, ndi Mounjaro chifukwa ndi jekeseni kamodzi pamlungu wa mahomoni omwe amasintha momwe timadyera, zomwe zimapangitsa kuti tiyambe kumva kukhuta komanso kuchepetsa chilakolako.

Koma mosiyana ndi Ozempic ndi Wegovy, omwe amatsanzira mahomoni amodzi oletsa njala (GLP-1), kapena Mounjaro, omwe amatsanzira mahomoni awiri (GLP-1 ndi GIP),retatrutideNdi molekyulu imodzi yomwe imatsanzira mahomoni atatu owongolera njala: GLP-1, GIP, ndi glucagon.Kachitidwe ka “katatu ka G” kameneka, monga momwe asayansi ena anachitchulira pamsonkhanowo, chikuwoneka kukhala ndi chiyambukiro champhamvu pa chikhumbo cha munthu ndi kukhutiritsidwa ndi chakudya.

Mu mayesero omwe adasindikizidwa mu NEJM, odwala omwe ali ndi kunenepa kwambiri omwe amapatsidwa mlingo wapamwamba kwambiri wa sabataretatrutide(12 mg) adataya pafupifupi mapaundi a 58 m'miyezi 11.Kulemera kwawo kunali kutsikabe ngakhale pamene mayeserowo adatha, kutanthauza kuti mayesero otalikirapo, akuluakulu omwe sanakwaniritsidwe angapereke zotsatira zochepetsera thupi.Wodwala aliyense pa mlingo wapamwamba kwambiri wa retatrutide anataya osachepera 5% ya kulemera kwa thupi lawo, ndipo gawo limodzi mwa magawo atatu a otenga nawo mbaliwo anataya 30% kapena kuposerapo kulemera kwawo.

Pakafukufuku wofananira wa retatrutide kwa odwala omwe ali ndi matenda a shuga amtundu wa 2 wofalitsidwa mu The Lancet, odwala adataya pafupifupi 17% ya thupi lawo m'miyezi isanu ndi inayi, zomwe ndi zodabwitsa kwambiri, chifukwa nthawi zambiri zimakhala zovuta kuti odwala omwe ali ndi T2D achepetse kulemera kofanana. monga anthu ena omwe ali ndi kunenepa kwambiri komanso kunenepa kwambiri.

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