China Supply Sarms Raw Sr9009 Stenabolic API

REV-ERBα ndi REV-ERBβ zolandilira nyukiliya ndizopondereza zolembera zomwe zimagwirizanitsa kayimbidwe ka circadian ndi njira za metabolic m'njira yodalira heme.SR9009 ndi REV-ERB agonist yomwe imawonjezera kuponderezedwa kwa majini olamulidwa ndi REV-ERBα ndi REV-ERBβ ndi IC50 makhalidwe a 670 ndi 800 nM, motsatira.1Kupyolera mu kutsegula kwa REV-ERB, SR9009 yasonyezedwa kuti imachepetsa zochitika za circadian locomotor panthawi yamdima komanso kusintha maonekedwe a ma gene gene mu hypothalami ya mbewa.1Mawonekedwe a circadian akuwonetsa mitundu yambiri ya majini a kagayidwe kachakudya m'chiwindi, minofu ya chigoba ndi minofu ya adipose inasonyezedwanso kuti inasinthidwa ndi mbewa zomwe zimawonekera ku SR9009, zomwe zimapangitsa kuti pakhale ndalama zowonjezera mphamvu. SR9009 (ip kawiri pa tsiku kwa masiku 30) adanenedwa kuti akuwonetsa kuchepa kwamafuta komanso kuwongolera bwino kwa dyslipidemia ndi hyperglycemia.1

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